Collagen is a protein that makes up connective tissue throughout the body. When collagen is overproduced, it results in connective tissue disorders, including Dupuytren disease, which affects the fingers and hands.
Overproduction of collagen in the hands from Dupuytren disease results in the formation of lumps called nodules and cords. This can cause the fingers and palm to tighten in a bent position, limiting the range of motion and function of the fingers.
Treatment for Dupuytren disease will depend on the severity of the condition. If detected early, injections and office-based procedures to break up the connective tissue may help. More advanced cases that affect the function of the hand may require surgery to cut through and break up the connective tissue.
